Zoloft (sertraline) contains an FDA Boxed Warning regarding an increased risk of suicidal thoughts and behaviors. Patients and their friends, family, or caregivers should monitor the patient for signs of suicidal thoughts and behaviors. Before you begin treatment with Zoloft, tell your doctor about:, All the medications you take, including prescription and nonprescription medications, herbals, and supplements., Your allergies., Your health history and current medical problems., Your pregnancy or breastfeeding status., The risk of serotonin syndrome is increased when taking SSRIs alone or with other medications that can cause serotonin syndrome such as triptans and serotonin norepinephrine reuptake inhibitors (SNRIs). Ask your doctor if you are unsure whether or not you take any of these medications., The risk of bleeding is increased when taking Zoloft with medications that can lead to bleeding such as aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs) like naproxen or ibuprofen, and warfarin., Zoloft may cause a mixed/manic episode in patients with bipolar disorder., Patients who have seizures should use caution when taking Zoloft., Patients who have untreated narrow angles should not take Zoloft as angle-closure glaucoma can occur., Patients who are at risk for QTc prolongation should use Zoloft with caution., Zoloft may cause sexual dysfunction including ejaculation problems, decreased desire for sex, and erectile dysfunction. All the medications you take, including prescription and nonprescription medications, herbals, and supplements., Your allergies., Your health history and current medical problems., Your pregnancy or breastfeeding status.