Chemical Name: RIFAXIMIN (rif-AX-i-min) Xifaxan (Rifaximin) is a prescription antibiotic used to treat several different conditions. It can be used for the following: Reduction of the occurrence of hepatic encephalopathy, Treatment of travelers' diarrhea, Treatment of irritable bowel syndrome with diarrhea (IBS-D) Xifaxan is an antibacterial medication that works by binding to bacterial DNA-dependent RNA polymerase, preventing bacteria from replicating their DNA and preventing bacterial growth. Xifaxan is thought to reduce the occurrence ofhepatic encephalopathyby inhibiting the growth of ammonia-producing bacteria. Xifaxan works in travelers' diarrhea and IBS-D by preventing the growth of certain harmful bacteria. Fact Table Formula C43H51N3O11 License US FDA Bioavailability Less than 4% Legal status Rx-Only Chemical Name Rifaximin Elimination half-life 6 hours Dosage (Strength) 200mg, 550mg Pregnancy Not Recommended Brands Xifaxan Protein binding 67.5% PubChem CID 6436173 MedlinePlus a604027 ChEBI 75246 ATC code A07AA11 DrugBank DB01220 KEGG D02554 Routes of administration By mouth (tablets)

Xifaxan (Rifaximin)

Xifaxan has different directions based on the condition being treated. Take it exactly as prescribed by your physician. That standard directions are: Hepatic encephalopathy: Take one Xifaxan 550 mg tablet by mouth twice daily., Travelers' diarrhea: Take one Xifaxan 200 mg tablet by mouth three times daily for three days., IBS-D: Take one Xifaxan 550 mg tablet three times daily for 14 days. This regimen may be repeated up to two times as prescribed by the physician.
If taking Xifaxan for travelers' diarrhea, it may not be effective for pathogens other thanEscherichia coli(E. coli). If diarrhea does not improve within 24 to 48 hours after starting Xifaxan, stop taking the medication and speak with your doctor about different antibiotic options. Do not use Xifaxan to treat diarrhea accompanied by fever or blood in the stool, as this may be a sign ofClostridium difficile-associated diarrhea. If you have a history of liver damage or liver failure, speak with your doctor before starting Xifaxan. Xifaxan has the potential for important drug-drug interactions, especially with medications that are used to prevent organ transplant rejections. Speak with your doctor or pharmacist about your other medications before starting Xifaxan.
Some of the most common side effects of Xifaxan include: Anorexia, Arthralgia, Decreased weight, Dizziness, Dysentery, Dyspnea, Nasal passage irritation, Nausea, Peripheral Edema, Pruritis, Pyrexia, Taste loss Please speak with your doctor or pharmacist for a complete list of side effects. The side effects experienced may vary based on which condition is being treated and for how long the medication is being taken. Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy.Read More....

Xifaxan (Rifaximin)

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