Wellbutrin XL (bupropion extended-release) is a medication prescribed to treat Major Depressive Disorder (MDD) and Seasonal Affective Disorder (SAD). MDD and SAD are mood disorders where a person experiences depressed moods (emptiness, sadness, etc.), decreased interest in normal activity, changes in sleep, changes in diet, low energy, difficulty concentrating, and similar symptoms that last for at least two weeks and often many months. Wellbutrin XL works by increasing the levels of neurotransmitters dopamine and norepinephrine in certain parts of the brain. By increasing these neurotransmitters consistently over several weeks, Wellbutrin XL normalizes levels of these neurotransmitters, helping return the mood to normal. Fact Table Formula C13H18ClNO License EU EMA, US FDA, US DailyMed Bioavailability Unknown Legal status Rx-Only Chemical Name Bupropion Elimination half-life 11–21 h Dosage (Strength) 150mg, 300mg Pregnancy Consult Doctor Brands Wellbutrin Protein binding 84% PubChem CID 444 MedlinePlus a695033 ChEBI 3219 ATC code N06AX12 DrugBank DB01156 KEGG D07591 Routes of administration By mouth

Wellbutrin XL (Bupropion)

Take Wellbutrin XL once daily at the same time each day. The normal dosage ranges from 150-450 mg. Note that other formulations of the active ingredient like Wellbutrin (bupropion immediate-release) and Wellbutrin SR (bupropion sustained-release) are not interchangeable with Wellbutrin XL.
Wellbutrin XL may increase the risk of seizures and should be used with caution in people with epilepsy or a history of seizures. In some short-term studies, antidepressants increased the risk of suicidal ideation and action in children and young adults. Since depression itself is associated with suicidal thoughts and behaviors, this should not be a reason to forgo treatment. Friends and family members should be alert to suicidal thoughts and actions in patients that are starting antidepressants, but this risk does not remain over the long-term. Adults over 24 did not show an increased risk.
Wellbutrin XL side effects may include: Abdominal Pain, Agitation, Chest pain, Constipation, Diarrhea, Dizziness, Dry Mouth, Flushing, Insomnia, Migraine, Migraine, Nausea, Nausea, Palpitation, Rash, Tremor Not everyone who takes Wellbutrin XL experiences every side effects, and most people only experience one or two. Speak with your doctor for a full list of possible side effects. Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy.Read More....

Wellbutrin XL (Bupropion)

Directions

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Side Effects