Every medication or a medical procedure has some side effects. These are usually very rare and do not affect everyone. Usually, your health care provider enlightens you about at the start of your treatment. Some of the common side effects that have been associated with this gel are as follows: Unusual drying out of the skin, Peeling of skin, Redness of skin, Burning sensation in the area where it is applied, Darkening or lightening of the treated area These side effects usually appear at the start of the treatment. Once, your body gets accustomed to the gel, these effects disappear. However, they may persist or start to get worse. Thus, it is important to inform your dermatologist as soon as any of these side effects are experienced.