Viekira (Ombitasvir/Paritaprevir/Ritonavir/Dasabuvir)

What are the active ingredients? Ombitasvir, Paritaprevir, Ritonavir, Dasabuvir What are the inactive ingredients? For a full list of inactive ingredients, see the package insert. Fact Table Formula Ombitasvir: C50H67N7O8, Paritaprevir: C40H43N7O7S, Ritonavir: C37H48N6O5S2, Dasabuvir: C26H27N3O5S License EU EMA, US FDA Bioavailability Varies, 70% Legal status RX Only Chemical Name Ombitasvir, Paritaprevir, Ritonavir, Dasabuvir Elimination half-life Ombitasvir: 21 – 25 hours, Paritaprevir: 5.5 hours, Ritonavir: 3-5 hours, Dasabuvir: 5.5- 6 hours Dosage (Strength) 12.5/75/50mg (28 ampules) Pregnancy Consult a doctor Brands Viekira Pak, Exviera,Norvir, Kaletra Protein binding Ombitasvir: 99.9%, Paritaprevir: 97-98.6%, Ritonavir: 98-99%, Dasabuvir: less than 99.5% PubChem CID Ombitasvir: 54767916, Paritaprevir: 45110509, Ritonavir: 392622, Dasabuvir: 56640146 MedlinePlus a614057 ChEBI Ombitasvir: 85183, Paritaprevir: 85188, Ritonavir: 45409, Dasabuvir: 85182 ATC code J05AP52 DrugBank Ombitasvir: DB09296, Paritaprevir: DB09297, Ritonavir: DB00503, Dasabuvir: DB09183 KEGG Ombitasvir: D10576, Paritaprevir: D10580, Ritonavir: D00427, Dasabuvir: D10553 Routes of administration By mouth

Who should avoid taking VIEKIRA? Viekira can have severe drug interactions with several drugs. Tell your doctor about every medication you take, including over the counter drugs. See Section 4 of the package insert for a full list of medications that must be avoided while taking Viekira., You should not take Viekira if: You are allergic to any of the ingredients listed in the package insert. You have severe liver disease., You are allergic to any of the ingredients listed in the package insert., You have severe liver disease. You are allergic to any of the ingredients listed in the package insert., You have severe liver disease. What are the risks associated with taking VIEKIRA? Viekira has a black box warning regarding hepatitis B infection. If you have ever had hepatitis B, taking Viekira can increase your risk of reactivation of the infection. Your doctor should monitor you closely if you have ever had hepatitis B., Viekira can have adverse effects on your liver. Your doctor should monitor your liver function periodically. They could decide to stop your treatment if you develop complications., Women who use birth control products containing ethinyl estradiol should stop taking their birth control before starting Viekira. Progesterone-only birth control products and non-hormonal products are safe options., If you are pregnant or considering becoming pregnant, discuss the risks with your physician. You should avoid becoming pregnant if your doctor as prescribed ribavirin as a combination treatment., Viekira therapy can lead to treatment resistance in patients who are infected with HIV. Your doctor should use additional HIV medications to reduce your risk of developing treatment-resistant HIV.

What are the common Viekira Pak side effects? Itching, Nausea, Insomnia, Fatigue What are the serious Viekira Pak side effects? Increased liver enzymes, Liver injury, Liver failure, Hepatitis B reactivation Other Considerations Compare the Viekira Pak price at Canada Pharmacy to your local drug store. Alex Covey studies chemistry and microbiology as an undergraduate before moving on to pharmacy school and completing his Pharm D.  His professional focus is on early phase clinical research but also has background experience in inpatient hospital, community pharmacy, and specialty compounding.Read More....