Tykerb is a prescription drug that your doctor may prescribe for the treatment of metastatic breast cancer. Tykerb is not a chemotherapy medication but may be used in addition to a chemotherapy regimen. Tykerb is typically prescribed by healthcare providers that specialize in the treatment of cancer. When you take this drug, extra monitoring may be required. Tykerb works by blocking a protein called endothelial growth factor receptor (EGFR). EGFR has several roles in the body, and in certain types of cancer, it can cause the replication of cancerous cells. Blocking EGFR helps to control the spread of cancer. Fact Table Formula C29H26ClFN4O4S License US FDA, EU EMA Bioavailability Variable Legal status Rx-only Chemical Name Lapatinib Elimination half-life 24 hours Dosage (Strength) 250mg Pregnancy Consult Doctor Brands Tykerb, Tyverb Protein binding More than 99% PubChem CID 208908 MedlinePlus a607055 ChEBI 49603 ATC code L01EH01 DrugBank DB01259 KEGG D08108 Routes of administration By mouth (tablets)

Tykerb (Lapatinib Ditosylate)

Take this drug exactly as prescribed by your healthcare team.
Common adverse reactions include: Alopecia, Anaphylaxis, Anorexia, Asthenia, Back pain, Decreased hemoglobin, Decreased left ventricular ejection fraction, Decreased neutrophils, Decreased platelet count, Diarrhea, Dyspepsia, Dyspnea, Epistaxis, Fatigue, Hepatotoxicity, Hypersensitivity reaction, Increased serum alanine aminotransferase, Increased serum aspartate aminotransferase, Increased serum bilirubin, Insomnia, Interstitial pulmonary disease, Limb pain, Nail disease, Nausea, Palmar-plantar erythrodysesthesia, Paronychia, Pneumonitis, Prolonged QT interval, Pruritus, Skin fissure, Skin rash, Stevens-Johnson syndrome, Stomatitis, Toxic epidermal necrolysis, Ventricular arrhythmia, Vomiting, Xeroderma

Tykerb (Lapatinib Ditosylate)

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