Twynsta (Telmisartan, Amlodipine)

Do not use Twynsta if you are pregnant. It could harm the unborn baby. Use effective birth control. Stop using Twynsta and tell your doctor right away if you become pregnant. You should not use Twynsta if you are allergic to amlodipine (Norvasc) or telmisartan (Micardis), or if you have diabetes and are taking aliskiren. Before you use Twynsta, tell your doctor about all your medical conditions and allergies. Also make sure your doctor knows if you are pregnant or breast-feeding. In some cases, you may not be able to use Twynsta, or you may need a dose adjustment or special precautions. Certain other drugs may interact with amlodipine and telmisartan or should not be used at the same time. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using. Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance. In rare cases, Twynsta can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.

Get emergency medical help if you have signs of an allergic reaction to Twynsta: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. In rare cases, Twynsta can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark colored urine. Call your doctor at once if you have: a light-headed feeling, like you might pass out; shortness of breath (even with mild exertion), swelling, rapid weight gain; new or worsened chest pain; pounding heartbeats or fluttering in your chest; tremors, muscle stiffness or twitching; or high potassium - nausea, slow or unusual heart rate, weakness, loss of movement. Common Twynsta side effects may include: swelling in your hands or feet; fast or pounding heartbeats; dizziness, drowsiness; flushing (warmth, redness, or tingly feeling); back pain; or nausea, diarrhea, stomach pain.