Your doctor may prescribe Tivicay for the treatment of HIV-1 infection. This medication should only be prescribed by healthcare professionals trained in the management of HIV and AIDS. Tivicay is usually not given on its own and will be given with other drugs that help to suppress HIV infection. These types of drugs are called Antiretroviral Therapy (ART). Tivicay works by shutting off a protein in HIV viral particles called integrase. Integrase is critical for the replication of HIV after it enters a human cell. Fact Table Formula C20H19F2N3O5 License US FDA, EU EMA Bioavailability n/a Legal status Rx-only Chemical Name Dolutegravir Elimination half-life ~14 hours Dosage (Strength) 50mg Pregnancy Consult Doctor Brands Tivicay, Tivicay PD Protein binding 98.9% PubChem CID 54726191 MedlinePlus a613043 ChEBI 76010 ATC code J05AJ03 DrugBank DB08930 KEGG D10066 Routes of administration By mouth

Tivicay (Dolutegravir)

The usual dose is 50 mg by mouth one to two times daily. The dose may be different depending on your individual circumstances.
The most common side effects of this drug include: Increased serum cholesterol, Abdominal distress, Abdominal pain, Abnormal dreams, Acute hepatic failure, Anxiety, Arthralgia, Depression, Diarrhea, Dizziness, Fatigue, Flatulence, Headache, Hepatitis, Hepatotoxicity, Hyperbilirubinemia, Hyperglycemia, Hypersensitivity reaction, Immune reconstitution syndrome, Increased creatinine phosphokinase, Increased HDL cholesterol, Increased LDL cholesterol, Increased serum alanine aminotransferase, Increased serum aspartate aminotransferase, Increased serum creatinine, Increased serum lipase, Increased serum triglycerides, Insomnia, Myalgia, Myositis, Nausea, Neutropenia, Pruritus, Renal insufficiency, Skin rash, Suicidal ideation, Suicidal tendencies, Upper abdominal pain, Vomiting, Weight gain

Tivicay (Dolutegravir)

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