Tirosint (levothyroxine sodium) contains an FDA Boxed Warning against its use for treating obesity or for weight loss. Doses that exceed daily hormonal requirements can cause serious or life-threatening toxicity. Before you start taking Tirosint, discuss the following with your doctor:, All the medications you take, including prescription and over-the counter medications, herbals, and supplements., Your allergies., Your health history and current medical problems., If you are pregnant or breastfeeding., The risk of cardiac events such as atrial fibrillation is increased with the use of Tirosint; therefore, elderly patients and patients with cardiovascular disease should take less than the full replacement dose., Tirosint should not be used to treat myxedema coma., Patients who have an acute adrenal crisis with adrenal insufficiency should not start taking Tirosint until they are treated with replacement glucocorticoids., Dosing should be properly titrated and carefully monitored to prevent hypothyroidism or hyperthyroidism., Tirosint may worsen blood sugar levels that result in increased antidiabetic medication or insulin requirements. Blood sugars should be carefully monitored during treatment and after stopping treatment with Tirosint., Taking too much Tirosint can decrease bone mineral density. All the medications you take, including prescription and over-the counter medications, herbals, and supplements., Your allergies., Your health history and current medical problems., If you are pregnant or breastfeeding.
