Tecfidera is a prescription medication used to treatmultiple sclerosis (MS). MS is a serious and progressive disease where the immune system attacks the protective layer of the nerve cells. Symptoms are varied and affect every part of the body. Tecfidera is approved to treat the following relapsing forms of MS: Clinically isolated syndrome, Relapsing-remitting disease, Active secondary progressive disease Tecfidera works by activating a cellular pathway called Nrf2, which is involved in the cellular response to oxidative stress. By activating this pathway, Tecfidera helps to treat MS. Tecfidera has been shown to reduce the number of relapses, delay the progression of disability, and slow the development of brain lesions. Tecfidera should only be prescribed by a physician that specializes in the treatment of MS. Fact Table Formula C6H8O4 License US FDA, EU EMA Bioavailability - Legal status Rx-Only Chemical Name Dimethyl fumarate Elimination half-life 12 hours Dosage (Strength) 120mg, 240mg Pregnancy Consult Doctor Brands Tecfidera Protein binding - PubChem CID 637568 MedlinePlus a613028 ChEBI 76004 ATC code L04AX07 DrugBank DB08908 KEGG D03846 Routes of administration By mouth
Tecfidera (Dimethyl Fumarate)
- The starting dose of Tecfidera is 120 mg by mouth twice daily for seven days. After seven days, the dose is increased to 240 mg by mouth twice daily. This medication comes as a delayed-release capsule and should not be crushed or chewed. Swallow the capsule whole with or without food.