Most medications can cause side effects which can be defined as an unwanted response to a medication when it is taken in normal doses. Side effects can range from mild or severe, temporary or permanent. Side effects are not experienced all patients who take this medication. Many side effects can be managed, and others may go away over time. Common side effects include skin burning, warmth, stinging, tingling, itching, redness, swelling, dryness, peeling, or irritation while using TAZORAC topical. If these side effects are excessive, talk to your doctor. You may need a lower dose or less frequent applications of TAZORAC. Serious side effects are not likely to occur. Stop using TAZORAC and seek emergency medical attention if you experience an allergic reaction (shortness of breath; closing of the throat; swelling of the lips, face, or tongue; or hives). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about additional side effects.