Get emergency medical help if you have signs of an allergic reaction to Tagrisso (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Call your doctor at once if you have: skin redness or purple spots that don't turn pale when pressed, and that still look red or bruised after 24 hours (may appear on your arms, legs, buttocks, or midsection); redness, rash, or blisters on the palms of your hands or the soles of your feet; new or worsening cough or trouble breathing; fast or pounding heartbeats; swelling in your lower legs, weight gain, feeling short of breath; a light-headed feeling, like you might pass out; low blood cell counts - fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet; or eye problems - vision changes, watery eyes, increased sensitivity to light, eye pain or redness.
