Synvisc One should only be injected by a healthcare practitioner., Avoid Synvisc One if you have a known allergy to hyaluronan., Synvisc One should not be injected into infected skin., Synvisc One is only approved for use in the knee., Discuss the risk of using Synvisc One if you have allergies to birds, feathers, or eggs., Do not use Synvisc if the packaging appears damaged or previously opened., If you are pregnant or considering becoming pregnant, discuss the risks of Synvisc with your physician., Synvisc is not approved for patients under the age of 21.