SPIRIVA RESPIMAT (Tiotropium) is an inhaled medication prescribed to treat asthma or chronic obstructive pulmonary disease (COPD). Patients with these conditions may have trouble breathing because of bronchospasms, which is an abnormal tightening of the muscles of the lungs. SPIRIVA RESPIMAT works by binding to receptors on the surface of muscle cells in the lung called muscarinic-receptors. When SPIRIVA RESPIMAT binds to these receptors, it causes lung muscles to relax, causing bronchodilation and making breathing easier. Fact Table Formula C19H22BrNO4S2 License US FDA, US DailyMed Bioavailability 19.5% Legal status Rx-Only Chemical Name Tiotropium Elimination half-life 5–6 days Dosage (Strength) Respimat 2.5mcg (60 puffs/30 doses/inhaler), 18mcg (30 doses/Handihaler), 18mcg (30 doses/rotacaps) Pregnancy Not Harmful Brands Spiriva Protein binding 72% PubChem CID 5487426 MedlinePlus a604018 ChEBI 90959 ATC code R03BB04 DrugBank DB01409 KEGG D01929 Routes of administration inhalation

Spiriva (Tiotropium)

The SPIRIVA RESPIMAT dosage is different depending on what you are using the medication for. Asthma: Two inhalations of SPIRIVA RESPIMAT 1.25 mcg once daily, COPD: Two inhalations of SPIRIVA RESPIMAT 2.5 mcg once daily You must take the medication every day for the full effect. SPIRIVA RESPIMAT is not a rescue inhaler, and should not be used to treat acute bronchospasm.
Some patients have reported bronchospasm while taking SPIRIVA RESPIMAT and similar medication. If you have a worsening of symptoms, stop taking the medication and call your doctor. Use SPIRIVA RESPIMAT with caution if you have narrow-angle glaucoma because this medication can make symptoms worse. Anticholinergics like SPIRIVA RESPIMAT can worsen urinary retention. Use with caution if you have a history of prostatic hyperplasia or bladder neck obstruction.
The most common adverse reactions while taking SPIRIVA are: Dry mouth, Dyspepsia, Non-specific chest pain, Pharyngitis, Rhinitis, Sinusitis, Upper respiratory tract infection, Urinary tract infection The side effects may be different depending on whether you are treating asthma or COPD. Speak with your doctor or pharmacist for the entire list of side effects that applies to you. Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy.Read More....

Spiriva (Tiotropium)

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