Rhofade is a prescription cream for topical use on the face. It is indicated for the treatment of persistent facial erythema associated withrosacea. Rosacea is a condition where someone has small red bumps on their face. It is more common in middle-aged women with fair skin. Without treatment, rosacea usually gets worse with time. Rhofade works by constricting blood flow to the area. Slowing and preventing blood flow helps to relieve symptoms of rosacea. Fact Table Formula C16H24N2O License US FDA Bioavailability - Legal status Rx-Only (topical cream) Chemical Name Oxymetazoline Elimination half-life 5–6 hours Dosage (Strength) 1% Pregnancy No Known Risks Brands Afrin, Ocuclear, Drixine, Rhofade Protein binding 56.7% to 57.5% PubChem CID 4636 MedlinePlus a617018 ChEBI 7862 ATC code D11AX27 DrugBank DB00935 KEGG D08322 Routes of administration Topical

Rhofade (Oxymetazoline HCI)

Apply a pea-sized amount to the affected area. Rhofade is usually applied to the entire face area while avoiding the eyes and lips. Wash hands thoroughly after using. Prime the bottle when using it for the first time by pumping three times. Do not apply the medication to the mouth, eyes, or vagina.
Use caution if you have a history of highblood pressureor other heart conditions like cardiovascular disease ororthostatic hypotension. Rhofade can constrict blood vessels and affect the cardiovascular system if absorbed into the circulation. Use caution if you have a history of Raynaud's phenomenon, scleroderma,Sjogren's syndrome, or thromboangiitis obliterans. Use caution if you have a history of narrow-angle glaucoma.

Rhofade (Oxymetazoline HCI)

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