Before starting therapy, women of childbearing age should have two negative pregnancy tests before taking the drug. Take this medication by mouth with a full glass of water, usually once daily or as directed by your doctor. Swallow this medication whole. Do not break, chew, or open the capsules. Dosage is based on your medical condition, response to therapy, and laboratory test results. Be sure to follow your doctor's directions carefully.Use this medication regularly in order to get the most benefit from it. Remember to take it at the same time each day. Inform your doctor if your condition persists or worsens.