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Retin-A Cream (Tretinoin) is a prescription medication that is applied to the skin and can treat acne vulgaris. Retin-A may also be used “off-label” for the palliation of fine wrinkles, treatment of roughness of facial skin, and to help with mottled hyperpigmentation. Tretinoin is a naturally occurring derivative of Vitamin A. When applied to the skin, it changes the way epithelial cells grow and differentiate. In people with acne, it decreases microcomedo formation and decreases the cohesiveness of follicular epithelial cells.

Retin A Cream (Tretinoin)

  • Apply a thin layer to the affected acne lesions once daily before bedtime or in the evening. Wash hands with soap and water after applying. Do not get the medication in the mouth or eyes. If contact with the mouth or eyes does occur, gently rinse with water.
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