Prezocobix is a prescription medication used for the treatment of human immunodeficiency virus (HIV) infection in adults. It is a combination drug that contains an antiviral and another drug to "boost" the effectiveness of the antiviral. Prezcobix works by inhibiting HIV protease, which is a necessary protein that helps HIV viral particles to replicate. By shutting down protease, Prezcobix prevents the HIV virus from spreading infection.