Fluphenazine is a First Generation Antipsychotic (FGA) used for the treatment of mental health disorders. Examples include bipolar disorder, schizophrenia, and schizoaffective disorder. It also has usage in the management of tics in people with Tourette’s syndrome. Fluphenazine is a piperazine phenothiazine FGA that works by increasing dopamine levels in certain areas of the brain. Regulating dopamine levels can improve psychotic symptoms.

Permitil (Fluphenazine)

The dosage is 2.5-10 mg by mouth divided into three or four dosages. Some patients may require much higher dosages, like 40 mg daily.
Common adverse reactions include Abnormal hepatic function tests, Agranulocytosis, Altered cerebrospinal proteins, Amenorrhea, Angioedema, Asthma, Atrioventricular block, Bizarre dream, Bladder paralysis, Bradycardia, Brain edema, Cataract, Corneal opacity, ECG changes, Eczema, EEG pattern changes, Eosinophilia, Erythema of skin, Excitement, Exfoliative dermatitis, Extrapyramidal reaction, Fecal impaction, Galactorrhea not associated with childbirth, Glaucoma, Gynecomastia, Hypertension, Hypotension, Immune thrombocytopenia, Impotence, Increased libido, Increased serum prolactin, Jaundice, Laryngeal edema, Leukopenia, Lupus-like syndrome, Maculopathy, Menstrual disease, Nasal congestion, Neuroleptic malignant syndrome, Neutropenia, Nonthrombocytopenic purpura, Pancytopenia, Paralytic ileus, Peripheral edema, Priapism, Pruritus, Restlessness, Rhabdomyolysis, Seborrhea, Skin photosensitivity, Skin pigmentation, Tachycardia, Urticaria, Weight changes, Withdrawal syndrome

Permitil (Fluphenazine)

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