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Otezla (Apremilast)
Otezla (apremilast) is an oral tablet taken by adults who have active psoriatic arthritis, plaque psoriasis and are candidates for phototherapy or systemic therapy, and oral ulcers related to Behçet’s Disease. Fact Table Formula C22H24N2O7S License US DailyMed, EU EMA, US FDA Bioavailability 73% Legal status Rx-Only Chemical Name Apremilast Elimination half-life 6–9 hours Dosage (Strength) 10mg, 20mg, 30mg Pregnancy Consult Doctor Brands Otezla Protein binding 73% PubChem CID 11561674 MedlinePlus a614022 ChEBI 78540 ATC code L04AA32 DrugBank DB05676 KEGG D08860 Routes of administration By mouth (tablets)

Otezla (Apremilast)

  • The instructions that come with your Otezla prescription should be followed. Talk to your doctor or pharmacist if you have any questions or concerns. Oteza comes in 10 mg, 20 mg, and 30 mg tablets. Because Otezla can cause gastrointestinal problems, it is recommended to steadily titrate Otezla until a dose of 30 mg by mouth two times a day is reached according to the suggested schedule: Day 1: 10 mg by mouth in the morning Day 2: 10 mg by mouth in the morning and 10 mg by mouth in the evening Day 3: 10 mg by mouth in the morning and 20 mg by mouth in the evening Day 4: 20 mg by mouth in the morning and 20 mg by mouth in the evening Day 5: 20 mg by mouth in the morning and 30 mg by mouth in the evening Day 6 and thereafter: 30 mg by mouth two times a day The dose may be adjusted based on kidney function.
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