Your healthcare provider may prescribe Ofev to treat certain lung conditions. It can be prescribed for the treatment of idiopathic pulmonary fibrosis (IPF), the treatment of chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype, or to slow lung damage in people with systemic sclerosis-associated interstitial lung disease (SSc-ILD). Ofev is a tyrosine kinase inhibitor. It blocks several signal molecules called kinases that are involved in these types of lung diseases. Fact Table Formula C31H33N5O4 License US FDA, EU EMA Bioavailability 4.7% Legal status Rx-only Chemical Name Nintedanib Elimination half-life 10–15 hrs Dosage (Strength) 100mg, 150mg Pregnancy Consult Doctor Brands Vargatef, Ofev Protein binding 97.8% PubChem CID 9809715 MedlinePlus a615009 ChEBI 85164 ATC code L01EX09 DrugBank DB09079 KEGG D10481 Routes of administration By mouth