WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS See full prescribing information for complete boxed warning. Women over 35 years old who smoke should not use NuvaRing., Cigarette smoking increases the risk of serious cardiovascular events from combination hormonal contraceptive (CHC) use. Before you begin using NuvaRing, tell your doctor:, If you have any allergies, About any medications you may take, Certain medications and herbal supplements, including CYP3A4, may diminish NuvaRing's effectiveness or increase breakthrough bleeding. Back-up or a different form of birth control is recommended in patients who take these medications. Ask your doctor if you do not know whether or not you take these medications., If you have any health conditions, About your pregnancy or breastfeeding status, Vascular risks are associated with use of the NuvaRing; discontinue use if these occur. Stop using NuvaRing at least 4 weeks before and continue through 2 weeks after major surgery. Women may begin using NuvaRing 4 weeks after delivery if they are not breastfeeding., Use of NuvaRing may induce Toxic Shock Syndrome, requiring immediate treatment., Use of NuvaRing may cause liver problems; discontinue use if you develop yellowing of your skin or whites of your eyes., Use of NuvaRing may cause high blood pressure. Regularly monitor your blood pressure. Your doctor may discontinue use of NuvaRing if your blood pressure significantly increases., A decreased glucose tolerance may be caused by the use of NuvaRing. Changes in lipids may be experienced by women with the use of NuvaRing. A different form of birth control should be considered in women with uncontrolled dyslipidemia., Women with high levels of triglycerides or a family history of high levels of triglycerides may be at a higher risk of pancreatitis., NuvaRing use may cause or worsen gallbladder disease., Tell your doctor if you experience a significant change in headaches. Your doctor may discontinue NuvaRing usage., NuvaRing may induce unusual vaginal bleeding or you may stop having periods. If you have any allergies, About any medications you may take, Certain medications and herbal supplements, including CYP3A4, may diminish NuvaRing's effectiveness or increase breakthrough bleeding. Back-up or a different form of birth control is recommended in patients who take these medications. Ask your doctor if you do not know whether or not you take these medications., If you have any health conditions, About your pregnancy or breastfeeding status Certain medications and herbal supplements, including CYP3A4, may diminish NuvaRing's effectiveness or increase breakthrough bleeding. Back-up or a different form of birth control is recommended in patients who take these medications. Ask your doctor if you do not know whether or not you take these medications.