Before you start treatment with Nexlizet, inform your doctor:, Of any medications you take. These include prescription and over-the-counter medications, vitamins, and herbal supplements. Avoid taking Nexlizet with simvastatin more than 20 mg or pravastatin more than 40 mg., Of your allergies., Of your medical conditions., If you are pregnant or plan to become pregnant., If you are breastfeeding or plan to breastfeed., Nexlizet can cause an increase in uric acid levels in the blood which can lead to gout., Nexlizet can cause tendon rupture. Call your doctor right away if you experience pain, swelling, or inflammation of your joints. Of any medications you take. These include prescription and over-the-counter medications, vitamins, and herbal supplements. Avoid taking Nexlizet with simvastatin more than 20 mg or pravastatin more than 40 mg., Of your allergies., Of your medical conditions., If you are pregnant or plan to become pregnant., If you are breastfeeding or plan to breastfeed.