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Nexlizet (bempedoic acid and ezetimibe) is used with diet and a statin medication to treat adults withheterozygous familial hypercholesterolemiaoratherosclerotic cardiovascular diseasewho need additional lowering of low-density lipoprotein cholesterol (LDL-C). Fact Table Formula C19H36O5 License US DailyMed, EU EMA Bioavailability - Legal status Rx-Only Chemical Name Bempedoic acid Elimination half-life 21±11 hrs Dosage (Strength) 180mg/10mg Pregnancy Contraindicated Brands Nexlizet Protein binding 99.3% PubChem CID 10472693 MedlinePlus a620020 ChEBI 149601 ATC code C10AX15 DrugBank DB11936 KEGG D10691 Routes of administration By mouth

Nexlizet (Bempedoic acid and Ezetimibe)

  • Nexlizet is available in a tablet that contains 180 mg of bempedoic acid and 10 mg of ezetimibe. The dose is to take one tablet by mouth once daily. It can be taken with or without food. The tablet should not be crushed or chewed. It should be swallowed whole. If you are taking bile acid sequestrants, take Nexlizet at least 2 hours before or 4 hours after taking bile acid sequestrants.
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