Nesina (alogliptin) is a prescription drug used for managing blood sugar levels in people withtype 2 diabetes. It works as a dipeptidyl peptidase-4 (DPP-4) inhibitor to control blood sugar levels. It is intended for use in individuals over the age of 18 and is typically prescribed alongside diet and exercise changes. Fact Table Formula C18H21N5O2 License US DailyMed Bioavailability 100% Legal status Rx-only Chemical Name Alogliptin Elimination half-life 12–21 hours Dosage (Strength) 6.25mg, 12.5mg, 25mg Pregnancy Pregnancy Category B - Caution advised Brands Nesina Protein binding 20% PubChem CID 11450633 MedlinePlus a613026 ChEBI 72323 ATC code A10BH04 DrugBank DB06293 KEGG D06553 Routes of administration Oral

Nesina (Alogliptin)

Nesina is available as a 6.25 mg, 12.5 mg, and 25 mg oral tablet. The usual dose is 25 mg, taken orally once a day with or without food. However, your doctor may adjust your dose based on your kidney function. Nesina should be taken as directed. Keep all medical appointments while on this medication to monitor your progress and adjust treatment as necessary.
Before starting your treatment with Nesina, inform your doctor about:, Any other medicines you are currently taking, including insulin or sulfonylureas, as they may increase the risk of hypoglycemia (low blood sugar)., Any medical conditions you are managing, such as pancreatitis, kidney disease, or liver problems., If you are pregnant, plan to become pregnant, or are breastfeeding. Nesina's impact on unborn or nursing babies isn't completely known, so discuss potential risks with your doctor., If you are going to have surgery., Contact your doctor if you develop symptoms of heart failure such as shortness of breath, rapid increase in weight, or swelling of your ankles or feet while taking Nesina., Nesina may cause severe and disabling joint pain. Call your doctor if you have severe joint pain., Nesina may cause allergic reactions. Seek immediate medical help if you have symptoms of a serious allergic reaction like rash, itching, swelling of the face, throat or tongue, dizziness, or trouble breathing., Nesina may increase the risk of liver failure. Symptoms of liver failure can include fatigue, loss of appetite, yellowing of the skin or eyes (jaundice), dark urine, light-colored stools, or swelling in your abdomen. If you experience any of these symptoms, contact your doctor immediately., The use of Nesina may increase your risk of developing acute pancreatitis. Symptoms may include severe abdominal pain, often accompanied by vomiting. If you experience these symptoms, contact your doctor immediately., Nesina has been linked to postmarketing reports of bullous pemphigoid, a rare skin condition that causes large, fluid-filled blisters. Symptoms may include itchy skin, rash, or blisters. In severe cases, it may require hospitalization. If you observe any signs of this condition, seek immediate medical attention. Any other medicines you are currently taking, including insulin or sulfonylureas, as they may increase the risk of hypoglycemia (low blood sugar)., Any medical conditions you are managing, such as pancreatitis, kidney disease, or liver problems., If you are pregnant, plan to become pregnant, or are breastfeeding. Nesina's impact on unborn or nursing babies isn't completely known, so discuss potential risks with your doctor., If you are going to have surgery.

Nesina (Alogliptin)

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