Motilium is a medication used to treat delayed gastric emptying that can cause symptoms like nausea, vomiting, bloating, fullness, and abdominal discomfort. Motilium works by blocking dopamine receptors in the gastrointestinal tract, which stimulates muscle contraction and increases food movement through the stomach and intestines. Motilium is not approved for use by the Food and Drug Administration in the United States but is available in other countries. Fact Table Formula C22H24ClN5O2 License US DailyMed Bioavailability Oral: 13–17% Legal status Rx-Only Chemical Name Domperidone Elimination half-life 7–9 hours Dosage (Strength) - Pregnancy Consult Doctor Brands Motilium Protein binding 92% PubChem CID 3151 MedlinePlus - ChEBI 31515 ATC code A03FA03 DrugBank DB01184 KEGG D01745 Routes of administration By mouth