Motegrity is a prescription prokinetic medication used for the treatment ofchronic idiopathic constipation CIC. Motegrity works to increase the movement of the colon muscle (peristalsis) to make bowel movements easier. The active ingredient Prucalopride targets a specific receptor in the colon to enhance the body's natural peristalsis process of waste elimination from the colon. You can buy Motegrity medication with a prescription at most pharmacies, and you may find your Motegrity cost is lower if you order your medication online from Canada. Fact Table Formula C18H26ClN3O3 License US FDA Bioavailability Over 90% Legal status Rx-Only Chemical Name Prucalopride Elimination half-life 18-20 hours Dosage (Strength) 1mg, 2mg Pregnancy Not Recommended Brands Motegrity Protein binding 30% PubChem CID 3052762 MedlinePlus a619011 ChEBI 135552 ATC code A06AX05 DrugBank DB06480 KEGG D09205 Routes of administration By mouth (Tablets)