The side effects that may occur while taking Lodine tablets include stomach pain, diarrhea, gas or bloating, upset stomach, weakness, dizziness,depression, chills, nervousness,constipation, vomiting and painful, or frequent urination. Stop taking Lodine and seek medical attention or call your doctor at once if you have any of these serious side effects which include: Chest pain, Weakness, Shortness of breath,, Slurred speech, Problems with vision or balance, Nausea, Stomach pain, Low fever, Loss of appetite, Dark urine, Clay-colored stools, Jaundice (yellowing of the skin or eyes), Rapid weight gain, Neck stiffness, Chills, Photosensitivity Other side effects include severe blistering, peeling, and red skin rash. There might be a case of coughing up blood or vomit that looks like coffee grounds.