Your healthcare provider may prescribe Letairis to treat pulmonary arterial hypertension (PAH), a condition characterized by high blood pressure in the arteries that supply the lungs. It belongs to a class of drugs known as endothelin receptor antagonists, which block the effects of endothelin, a substance that narrows blood vessels. Letairis helps to relax and widen the blood vessels in the lungs by inhibiting the action of endothelin. This reduces the strain on the heart and improves exercise capacity in individuals with PAH. Fact Table Formula C22H22N2O4 License US FDA, EU EMA Bioavailability Undetermined Legal status Rx-Only Chemical Name Ambrisentan Elimination half-life 15 hours (terminal) Dosage (Strength) 10mg Pregnancy Consult Doctor Brands Letairis Protein binding 99% PubChem CID 6918493 MedlinePlus a612023 ChEBI 135949 ATC code C02KX02 DrugBank C02KX02 KEGG D07077 Routes of administration By mouth
Letairis (Ambrisentan)
- The usual dosage is 5 mg by mouth once daily. The dosage can be increased every four weeks. Letairis is typically taken orally once daily, with or without food. The dosage may vary depending on the individual's response to treatment and other factors, as determined by a healthcare professional. Take this drug exactly as prescribed. If a dose is missed, it should be taken as soon as possible unless it is close to the next scheduled dose.
