Latuda (Lurasidone) Latuda is a medication prescribed to treat several different psychiatric disorders. The conditions it is indicated to treat include: Depressive episode associated with bipolar 1 disorder (alone), Depressive episode associated with bipolar 1 disorder (in combination with lithium or valproic acid), Schizophrenia Bipolar disorderandschizophreniaare psychiatric disorders where there is a problem with the messaging systems in the brain. Symptoms may manifest by affecting mood or thought and may impair cognition. Latuda works by blocking certain receptors on the surface of brain cells that receive signals from other brain cells. Latuda blocks receptors for dopamine (D2) and serotonin (5HT2A). By blocking these signals in certain parts of the brain, Latuda helps to restore normal thoughts, moods, and cognition. Fact Table Formula C28H36N4O2S License US FDA, US DailyMed Bioavailability 9–19% (oral) Legal status Rx-Only Chemical Name Lurasidone Elimination half-life 18–40 hours Dosage (Strength) 20mg - 120mg Pregnancy Not recommended Brands Latuda Protein binding 99% PubChem CID 213046 MedlinePlus a611016 ChEBI 70735 ATC code N05AE05 DrugBank DB08815 KEGG D04820 Routes of administration By mouth

Latuda (Lurasidone)

The starting dose of Latuda is 20-40 mg taken by mouth once daily. The dose is increased until the lowest effective dose is found, typically 20-160 mg once daily. The daily dose may be reduced in patients with impaired kidney or liver function.
Latuda may increase the risk of death in elderly patients being treated for dementia-related psychosis. Taking Latuda or other antipsychotic medications for long periods may cause an irreversible movement disorder calledtardive dyskinesia (TD). TD is characterized by stiff and jerky movements of the face and body that cannot be controlled. Latuda and other antipsychotics may increase the risk of metabolic disorders like diabetes mellitus and dyslipidemia, and lead to weight gain. Latuda and other antipsychotic drugs may raise levels of prolactin in the blood, which could lead to gynecomastia. Speak to your doctor for a full list of warnings and precautions.
Common adverse reactions of Latuda include: Akathisia, Extrapyramidal symptoms, Insomnia, Nausea, Somnolence, Vomiting, Weight increase Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy.Read More....

Latuda (Lurasidone)

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