Common Kreon side effects may include: Stomach pain, Gas, Upset stomach, Diarrhoea, Frequent or abnormal bowel movements, Rectal itching, Headache, Runny or stuffy nose, Sore throat, Changes in your blood sugar, Blurred vision, Dry mouth, Flushed, dry skin, Fruit-like breath odour, Increased hunger, Headache, Increased thirst, Increased urination, Sweating, Unexplained weight loss, Vomiting, Itching with or without a rash, Allergic reactions (which may be severe), Severe or long-lasting abdominal pain (Fibrosing colonopathy). Bowel disorder, Severe or unusual stomachache, Vomiting, Bloating, Diarrhea, Constipation