Before you begin treatment with Keflex, you should tell your doctor about:, All the medications you take, Your allergies, Your health history and current health problems, Your pregnancy or breastfeeding status, Keflex can cause serious allergic reactions, including anaphylaxis. You should seek emergency care immediately if you have trouble breathing, a rash, or swelling of the face, tongue, or throat., Keflex can cause Clostridium difficile-associated diarrhea., Anemia can occur during treatment with cephalosporins., Seizures can occur with cephalosporins, especially in patients with kidney problems., Cephalosporins can cause prolonged prothrombin time, especially in patients with kidney or liver problems, malnutrition, or in patients receiving a protracted course of antibiotics and in patients taking anticoagulants., Long-term use of Keflex can cause an overgrowth of bacteria that has become resistant to the antibiotic. All the medications you take, Your allergies, Your health history and current health problems, Your pregnancy or breastfeeding status