Speak with your doctor before starting JARDIANCE if you have a history of low blood pressure (hypotension) or are taking diuretics for heart or fluid conditions. JARDIANCE can change the amount of fluid in your body, potentially worsening these conditions. JARDIANCE and similar medications have been linked to a serious condition called diabetic ketoacidosis (DKA). During DKA, the blood sugar is very high but cannot be utilized by the cells of the body, so instead, they break down fat molecules. DKA is a medical emergency and signs and symptoms can include fruit-scented breath, higher thirst, nausea and vomiting, stomach pain, weakness, and confusion. Speak with your doctor if you have a history of kidney problems before starting JARDIANCE. While taking JARDIANCE, you may have an increased risk of urinary tract infection. JARDIANCE and similar medications cause the kidney to excrete higher amounts of glucose, which can act as food for bacteria. JARDIANCE may increase LDL cholesterol, so you should be monitored for changes while taking this medication.