Your doctor may prescribe the powerful immunosuppressant Imuran to treat various types of immune system disorders. Examples of diseases it can treat include uveitis, rheumatoid arthritis, sarcoidosis, solid organ transplant rejection, immune thrombocytopenia, hepatitis, and Crohn's disease. Imuran is converted into mercaptopurine in the body. Mercaptopurine incorporates into the DNA of replicating human cells and prevents excess replication that can cause disease. Fact Table Formula C9H7N7O2S License US FDA Bioavailability 60±31% Legal status RX Only Chemical Name Azathioprine Elimination half-life 26–80 minutes Dosage (Strength) 50mg Pregnancy Consult Doctor Brands Azasan, Imuran Protein binding 20–30% PubChem CID 2265 MedlinePlus a682167 ChEBI 2948 ATC code L04AX01 DrugBank DB00993 KEGG D00238 Routes of administration By mouth

Imuran (Azathioprine)

The dosage is adjusted for the person taking it and the needs of their disease. Do not adjust this medication without speaking with your doctor.
Adverse reactions to Imuran include: Acute myelocytic leukemia, Alopecia, Anemia, Aplastic anemia, Arthralgia, Bone marrow depression, Cholestasis, Diarrhea, Drug-induced hypersensitivity reaction, Erythema nodosum, Fever, Gastrointestinal hypersensitivity, Hemophagocytic lymphohistiocytosis, Hemorrhage, Hepatic sinusoidal obstruction syndrome, Hepatosplenic T-cell lymphomas, Hepatotoxicity, Hypersensitivity pneumonitis, Infection, Interstitial pneumonitis, JC virus infection, Leukopenia, Macrocytic anemia, Malignant lymphoma, Malignant neoplasm of skin, Malignant solid tumor, Nausea and vomiting, Negative nitrogen balance, Neoplasm, NK cell deficiency, Pancreatitis, Pancytopenia, Progressive multifocal leukoencephalopathy, Skin rash, Steatorrhea, Sweet's syndrome, Thrombocytopenia

Imuran (Azathioprine)

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