Most medications can cause side effects which can be defined as an unwanted response to a medication when it is taken in normal doses. Side effects can range from mild or severe, temporary or permanent. Side effects are not experienced all patients who take this medication. Many side effects can be managed, and others may go away over time. Common side effects may include muscle weakness, dizziness, cramps, thirst, stomach pain, upset stomach, vomiting, diarrhea, loss of appetite, headache and hair loss. Serious side effects may include eye pain,vision problems; dry mouth, thirst, nausea, vomiting; feeling weak, drowsy, restless, or light-headed; fast or uneven heartbeat; muscle pain or weakness; numbness or tingly feeling; a red, blistering, peeling skin rash; or nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Get emergency medical attention if you have any signs of an allergic reaction (hives; difficulty breathing; swelling of your face, lips, tongue, or throat). Stop using Hydrochlorothiazide immediately and call your doctor at once if you experience any of the above noted serious side effects. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about additional side effects that you may experience.