Before starting treatment with Frova, you should inform your doctor of:, All the medications you take, including prescription, nonprescription, vitamins, and herbal supplements, Your allergies, Your medical history and current medical conditions, Your pregnancy or breastfeeding status, Heart attack or other cardiac events can occur after taking Frova., Frova can cause heart arrhythmias that can be life-threatening., Pain, tightness, pressure, and heaviness in the chest, throat, neck, and jaw can occur after taking Frova. These effects are generally not related to the heart. However, you should talk to your doctor about your risks for cardiac events., Cerebral bleeding, subarachnoid bleeding, stroke, or other cerebrovascular events that can be life-threatening can occur in patients treated with Frova., Frova can cause non-coronary vasospastic events like peripheral vascular ischemia, gastrointestinal vascular ischemia and infarction (causing stomach pain and bloody diarrhea), splenic infarction, and Raynaud's syndrome. Blindness that may be permanent or partial vision loss can also occur., Taking too much Frova can cause or worsen headaches., Frova can cause serotonin syndrome, especially if taken with other medications that can cause serotonin syndrome. Seek medical care right away if you develop agitation, hallucinations, rapid heart rate, unstable blood pressure, coordination problems, overactive reflexes, nausea, vomiting, or diarrhea., Frova can cause serious elevations in blood pressure., Frova can cause serious allergic reactions. Seek emergency care right away if you develop trouble breathing, swelling of your face, lips, tongue, or throat, a rash, or fast heart rate. All the medications you take, including prescription, nonprescription, vitamins, and herbal supplements, Your allergies, Your medical history and current medical conditions, Your pregnancy or breastfeeding status