Before you begin treatment with Florinef, discuss the following with your doctor:, Any allergies you may have, Any medications you take, including prescription, nonprescription, vitamins, and herbal supplements, Any medical conditions you have, If you are pregnant or breastfeeding, Florinef can mask some signs of infections. New infections may occur during treatment with Florinef., Using Florinef for an extended period of time can cause cataracts or glaucoma and increases the risk for secondary fungal or viral eye infections., Florinef can cause high blood pressure, salt and water retention, and loss of potassium., You should avoid receiving the smallpox vaccine during treatment with Florinef. Talk to your doctor or pharmacist before receiving any vaccinations., Florinef should be used with caution if you have tuberculosis., Florinef should be used with caution if you have ocular herpes simplex as it can cause perforation of the cornea., Florinef can cause psychic derangements such as euphoria, sleep problems, mood changes, personality changes, severe depression, and psychotic episodes., If you have a blood disorder in which your blood's ability to clot is impaired and you take aspirin, caution should be used during treatment with Florinef., Florinef should be used with caution if you have nonspecific ulcerative colitis, diverticulitis, fresh intestinal anastomosis, active or latent peptic ulcer, kidney problems, high blood pressure, osteoporosis, acute glomerulonephritis, vaccinia, varicella, exanthema, Cushing's syndrome, infections that are resistant to antibiotics, diabetes, congestive heart failure, chronic kidney inflammation, blood clotting tendencies, blood clot in the vein, convulsive disorders, metastatic carcinoma, and myasthenia gravis., The effect of Florinef may be enhanced if you have hypothyroidism or cirrhosis., Growth and development should be monitored in infants and children who take Florinef for an extended period of time., Florinef should not be abruptly discontinued. Any allergies you may have, Any medications you take, including prescription, nonprescription, vitamins, and herbal supplements, Any medical conditions you have, If you are pregnant or breastfeeding