The most common adverse reactions are: Acute myocardial infarction, Anaphylaxis, Aphthous stomatitis, Application site atrophy, Application site erythema, Application site irritation, Application site vesicles, Blurred vision, Body odor, Burning sensation of skin, Cataract, Cerebrovascular accident, Constipation, Coronary thrombosis, Decreased appetite, Depression, Dermatitis, Diarrhea, Dizziness, Drowsiness, Drug reaction with eosinophilia and systemic symptoms, Dysgeusia, Eczema, Exfoliative dermatitis, Facial edema, Gastritis, Gastroenteritis, Gastrointestinal hemorrhage, Gastrointestinal inflammation, Gastrointestinal perforation, Gastrointestinal ulcer, Hyperhidrosis, Hyperkinetic muscle activity, Hypersensitivity reaction, Hypertension, Hypoesthesia, Increased serum creatinine, Increased serum transaminases, Laryngismus, Laryngitis, Lethargy, Lip edema, Local skin discoloration, Lower limb cramp, Nausea, Neck stiffness, Oral mucosa ulcer, Otalgia, Palpitations, Pharyngeal edema, Pharyngitis, Rectal hemorrhage, Skin discoloration, Stevens-Johnson syndrome, Tongue edema, Toxic epidermal necrolysis, Upper abdominal pain, Urticaria, Visual disturbance, Vomiting, Xeroderma, Xerostomia