Estalis is a prescription medication that treats menopausal symptoms in women. It is a combination of two hormones, estradiol and norethindrone acetate, which help replace the hormones the body stops making during and after menopause. Estradiol is a synthetic estrogen replacement, and norethindrone is a synthetic progesterone. Fact Table Formula C22H28O3.C18H24O2 License US DailyMed Bioavailability 50% - 100% Legal status Rx-Only Chemical Name Estradiol/norethisterone acetate Elimination half-life 12-14 hours Dosage (Strength) LD 0.5/0.1mg 3 months, LD 1.0/0.5mg 1 month,  1.0/0.5mg 3 months Pregnancy Consult Doctor Brands Estalis Protein binding 37- 61% PubChem CID none MedlinePlus a601041 ChEBI - ATC code G03FA01 DrugBank - KEGG - Routes of administration By mouth

Estalis (Estradiol / Norethindrone)

Estalis is a patch that is applied to the skin. Your doctor determines the dose based on your needs and treatment response. The dosage forms include: Estalis 140/50, Estalis 250/50 Estalis patches are typically applied twice a week, and the patch should be left on the skin for 3-4 days of the seven-day cycle. Alternate application sites each time.
Common adverse reactions may include: Abdominal pain, Abnormal pap smear, Acne vulgaris, Application site reaction, Arthralgia, Back pain, Breast hypertrophy, Bronchitis, Constipation, Depression, Diarrhea, Dizziness, Dysmenorrhea, Dyspepsia, Emotional lability, Endometrial hyperplasia, Flatulence, Flu-like symptoms, Gastroenteritis, Headache, Hypermenorrhea, Infection, Insomnia, Leukorrhea, Limb pain, Mastalgia, Menstrual disease, Nasopharyngitis, Nausea, Nervousness, Ovarian cyst, Pain, Peripheral edema, Pharyngitis, Postmenopausal bleeding, Respiratory tract disease, Rhinitis, Sinusitis, Skin rash, Upper respiratory tract infection, Uterine fibroids, Vaginal hemorrhage, Vaginitis, Viral infection, Vulvovaginal candidiasis, Weakness, Weight gain

Estalis (Estradiol / Norethindrone)

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