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Fact Table Formula C96H120N12Na6O21 License EU EMA Bioavailability 60% Legal status US: RX Only Chemical Name Sacubitril / Valsartan Elimination half-life 1.4-11 hours Dosage (Strength) 24/25mg (56 or 168 tablets), 49/51mg (56 or 168 tablets), 97/103mg (56 or 168 tablets) Pregnancy Consult a doctor Brands Entresto Protein binding 97% PubChem CID 71449007 MedlinePlus a682462 ChEBI - ATC code C09DX04 DrugBank DB09292, DB00177 KEGG D10226 Routes of administration By mouth (tablets)

Entresto (Sacubitril/Valsartan)

  • The recommended starting dose of Entresto is one tablet of 49 mg/51 mg twice daily, except in certain situations. The dose should be doubled at 2-4 weeks to the target dose of one tablet of 97 mg/103 mg twice daily, as tolerated by the patient. Entresto may be administered with or without food. The tablets must be swallowed with a glass of water.
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