Before starting treatment for your knee osteoarthritis with Durolane, be sure to discuss the following with your doctor:, Your allergies, All the medications take, Your health problems, If you are pregnant or breastfeeding, Strict aseptic administration technique is recommended when using Durolane., Each Durolane injection is for single use only and must be used once the package is opened. Durolane injections should not be re-used. The syringes and any unused Durolane should be disposed of., Avoid using Durolane if the syringe blister package is opened or damaged., Avoid using skin disinfectants that contain quaternary ammonium salts., Durolane should not be injected into blood vessels, outside of the joint, or into the synovial tissue or capsule., Caution with Durolane should be used if you have pre-existing chondrocalcinosis as the injection could cause an attack., You should not participate in strenuous or prolonged weight-bearing activities within 48 hours of receiving a Durolane injection., You may experience pain or swelling of the affected knee joint after receiving a Durolane injection., Durolane should be stored at temperatures between 32°F-86° F (0°C-30° C). Your allergies, All the medications take, Your health problems, If you are pregnant or breastfeeding