Deplin is a prescription medical food that is used to increase folate levels in the treatment ofMajor Depressive Disorder (MDD)or hyperhomocysteinemia in patients with schizophrenia. Deplin is the brand name for folate, which is usually made in the body but can be deficient in some conditions. Folate is responsible for helping to create DNA, RNA, and other essential molecules in the body. Deplin replaces folate that cannot be absorbed from the diet alone. Fact Table Formula C20H25N7O6 License US FDA Bioavailability - Legal status US: OTC Chemical Name Levomefolate Calcium Elimination half-life 3 hour Dosage (Strength) 7.5mg, 15mg Pregnancy Consult Doctor Brands Deplin Protein binding 98% PubChem CID 444412 MedlinePlus - ChEBI 136009 ATC code B03BB51 DrugBank DB11256 KEGG D09353 Routes of administration Oral
Deplin (Levomefolate Calcium)
- For depression, the usual dose is one Deplin 15 mg capsule or one to two 7.5 mg capsules once daily in addition to standard antidepressant therapy. For schizophrenia, the dosage is also 7.5-15 mg by mouth once daily. Only use Deplin under the supervision of a physician or other healthcare professional. Deplin is a medical food that should only be used by people who cannot obtain the nutrient with normal diet modifications. Store Deplin at room temperature, protected from heat, light, and moisture.
