Call your doctor if any of the following side effects appear on the administration of Denavir cream. Allergic reaction leading to hives, difficulty in breathing, swelling of the face, lips, tongue or throat, Numbness or tingling where the cream is applied, Burning or stinging over the application site, Discoloration of the skin when the cream is applied, Headache, Changes in the sense of taste, Severe skin redness, itching, rash or pain Fact Table Formula C10H15N5O3 License US FDA Bioavailability 1.5% (oral), negligible (topical) Legal status RX Only Chemical Name Penciclovir Elimination half-life 2.2-2.3 hours Dosage (Strength) 1% (30 grams), 2.5% (50 grams) Pregnancy Consult a doctor Brands Denavir Protein binding less than 20% PubChem CID 135398748 MedlinePlus a697027 ChEBI 7956 ATC code D06BB06, J05AB13 DrugBank DB00299 KEGG D05407 Routes of administration Topical