Contrave (Bupropion/Naltrexone)

Each extended-release tablet contains 8 mg of naltrexone hydrochloride (HCl) and 90 mg of bupropion HCl. The inactive ingredients include microcrystalline cellulose, hydroxypropyl cellulose, lactose anhydrous, L-cysteine hydrochloride, crospovidone, magnesium stearate, hypromellose, edetate disodium, lactose monohydrate, colloidal silicon dioxide, Opadry II Blue, and FD and C Blue #2 aluminum lake.

Contrave has a FDA Boxed Warning regarding an increased risk of suicidal thoughts or behavior. Patients who are taking Contrave should be monitored for suicidal thoughts or behaviors., Before you start treatment with Contrave, it's important that you tell your doctor about:, All the medications you take, Your allergies, Your health history and current health problems, Your pregnancy or breastfeeding status, While quitting smoking, neuropsychiatric adverse events such as mood changes, psychosis, hallucinations, paranoia, agitation, and anxiety can occur in patients taking Contrave. If any of these effects occur, patients should contact their doctor right away., The risk of seizures may be reduced with adherence to the dosing schedule and avoiding a high-fat meal when taking Contrave., Heart rate and blood pressure can increase with the use of Contrave., Liver damage can occur with the use of Contrave., Glaucoma can occur with the use of Contrave., Low blood sugar may occur with the use of antidiabetic medications and weight loss that can occur with Contrave. All the medications you take, Your allergies, Your health history and current health problems, Your pregnancy or breastfeeding status

The most common Contrave side effects include nausea, constipation, headache, vomiting, dizziness, sleep problems, dry mouth, and diarrhea. However, these are not all the side effects that can occur. Call your doctor right away if you develop bothersome or persistent side effects.