Complera contains a FDA Boxed Warning regarding severe worsening of hepatitis B virus (HBV) in patients with HIV-1 and HBV who stopped taking medications containing emtricitabine and/or tenofovir disoproxil fumarate. Before you start treatment with Complera, you should discuss the following with your doctor:, About all the medications you take, including prescription and over-the-counter, Your allergies, Your medical history and health problems, Your pregnancy or breastfeeding status, Allergic reactions, including fever, rash, blisters, and swelling, can occur with the use of Complera., Complera can cause liver problems in patients. The risk is greater in patients who have hepatitis B or C or elevated liver enzymes., Complera can cause depression and other mood changes., Kidney problems can occur with the use of Complera and should not be given to patients with moderate or severe kidney problems., Bone mineral density can be decreased by Complera., Taking Complera with medications that can prolong the QTc interval can increase the risk of Torsade de Pointes, a serious abnormal heart rhythm., Lactic acidosis and liver enlargement with extra fat in the liver that can be fatal may occur with the use of Complera., Immune system problems can occur with the use of Complera. About all the medications you take, including prescription and over-the-counter, Your allergies, Your medical history and health problems, Your pregnancy or breastfeeding status
