Compazine is a medication commonly prescribed to treat nausea and vomiting but can also be used for migraine treatment. Compazine was initially used as an antipsychotic agent but is no longer used for this purpose. Compazine works by blocking dopamine receptors in the brain responsible for feelings of nausea. Compazine blocks the release of hormones that cause nausea and vomiting. Fact Table Formula C20H24ClN3S License US FDA Bioavailability Unknown, but presumed substantial Legal status Rx-only Chemical Name Prochlorperazine Elimination half-life 4–8 hours Dosage (Strength) 5mg Pregnancy Consult Doctor Brands Compazine, Stemetil Protein binding 91–99% PubChem CID 4917 MedlinePlus a682116 ChEBI 8435 ATC code N05AB04 DrugBank DB00433 KEGG D00493 Routes of administration By mouth
Compazine (Prochlorperazine)
- Compazine is available in 5 mg and 10 mg tablets. The normal dose of Compazine is 5 to 10 mg by mouth every 3 to 4 hours as needed for nausea and vomiting. The maximum dose of Compazine in one day is 40 mg. Take Compazine with food or water as tolerated.
