Colestid may inhibit absorption of other medications. Take other medications at least one (1) hour before or four (4) to six (6) hours after colestipol. Be sure to continue taking medication even if you feel your condition has improved. Colestid may not be suitable for people with chronic constipation, hemorrhoids, or kidney disease. Colestid can inhibit absorption of certain nutrients, includingfolic acid, and fat-soluble vitamins A, D, E, and K. You may want to discuss potential nutritional deficiencies with your doctor.