CLOMID (clomiphene) is a medication prescribed to treat ovulatory dysfunction in women desiring to become pregnant. CLOMID is most likely to be effective in patients suffering from amenorrhea-galactorrhea syndrome, psychogenic amenorrhea, post-oral-contraceptive amenorrhea, and polycystic ovary syndrome (PCOS). CLOMID works by binding to estrogen receptors in the hypothalamus, an area of the brain responsible for releasing cyclic hormones. By binding to estrogen receptors, clomiphene prevents the natural recycling of estrogen, which causes other hormones involved in fertility to surge and the release of eggs from the ovaries. Fact Table Formula C26H28ClNO License - Bioavailability More than 90% Legal status Rx-Only Chemical Name Clomifene Elimination half-life 5–6 days Dosage (Strength) 50mg Pregnancy Not recommended Brands Clomid Protein binding Not Available PubChem CID 2800 MedlinePlus a682704 ChEBI 3752 ATC code G03GB02 DrugBank DB00882 KEGG D07726 Routes of administration By mouth (tablets)
Clomid (Clomiphene)
- The usual starting dose is to take one CLOMID 50 mg tablet by mouth daily for five days. Begin taking CLOMID on or around the fifth day of the menstrual cycle if bleeding is induced by progestin or spontaneously occurs before therapy. Treatment may begin at any time if there has been no recent uterine bleeding. In some patients, the dose may be increased to CLOMID 100 mg by mouth once daily for five days if ovulation does not occur with the CLOMID 50 mg once daily dose. For patients who experience adverse effects, the dose may be decreased from 12.5 to 25 mg by mouth once daily. A cycle of CLOMID may be repeated 30 days after the prior cycle. CLOMID should not be taken for longer than six cycles. Ask your doctor when to take CLOMID and how it should be used. Take CLOMID exactly as prescribed by your doctor and do not deviate from those instructions unless your doctor changes the prescription.
