Chloroquine malaria treatment is a medication approved to prevent and treat malaria infection. It can also be prescribed to treatextraintestinal amebiasis. Chloroquine is an anti-infective agent that works by binding to DNA and RNA polymerase in parasites. By blocking these proteins, chloroquine interferes with normal parasite metabolism. It also concentrates within the acid vesicles of parasites, causing a pH shift that impairs their growth.

Chloroquine

The dosage of chloroquine depends on what is being treated. Take chloroquine exactly as prescribed by your doctor. The usual doses are: Prevention of malaria: One Chloroquine 500 mg tablet by mouth once weekly, 1-2 prior to traveling to an area endemic with malaria. Continue weekly dosages for four weeks after leaving the area., Treatment of extraintestinal amebiasis: Two 500 mg (1000 mg total) on days 1-2, followed by 500 mg once daily for 2-3 weeks, Treatment of malaria: Two 500 mg (1000 mg total) by mouth on day 1, then 500 mg 6, 24, and 48 hours after the first dose. Chloroquine is available in Chloroquine 250 mg and Chloroquine 500 mg.
Common side effects may include: Abdominal cramps, Blurred vision, Changes in hair color, Changes in mood, Confusion, Darkening of skin, Depression, Diarrhea, Easy bruising, Hair loss, Headache, Hearing changes, Liver disease, Muscle fatigue, Nausea, Paling of lips or skin, Shortness of breath, Signs of severe infection, Sun sensitivity, Swelling, Tiredness, Unwanted movements, Vomiting, Weakness, Worsening of skin conditions Drug [package insert].Eatontown, NJ: Westward; 2009.

Chloroquine

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