WARNING: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS See full prescribing information for complete boxed warning Non-steroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use CAMBIA is contraindicated in the setting of coronary artery bypass graft (CABG) surgery NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events Before you start taking Cambia for your migraines, inform your doctor of:, All the prescription and over-the-counter medications you take, including vitamins and supplements, Cambia can interact with other medications that also increase the risk of bleeding including warfarin, aspirin, selective serotonin reuptake inhibitors, and serotonin-norepinephrine reuptake inhibitors, Cambia can interact with certain other blood pressure medications, causing kidney problems, Cambia can interact with certain fluid pills, Cambia can increase digoxin levels, Your allergies, Your health problems, Your pregnancy or breastfeeding status and plans, Prolonged use of NSAIDs like Cambia can increase the risk for a heart attack, stroke, or other cardiovascular thrombotic events., Taking NSAIDs like Cambia can cause severe inflammation, bleeding, ulceration, or perforation of the esophagus, stomach, or intestines. These effects can be life threatening., Cambia can cause liver damage., Cambia can cause high blood pressure or worsen existing high blood pressure. Check your blood pressure regularly., Cambia can worsen heart failure and swelling., Cambia can cause kidney damage., Cambia can cause increased potassium levels., Cambia can cause severe allergic reactions. Seek emergency care immediately if you have shortness of breath, swelling of your face, lips, tongue, or throat, rash, itching, or rapid heart rate., Cambia can worsen asthma in patients who have aspirin-sensitive asthma., Cambia can cause severe skin reactions. Seek emergency care if you develop a rash, itching, or other signs of a skin reaction., Taking too much Cambia can cause headaches., Cambia can harm an unborn baby and should not be taken starting at 30 weeks gestation., Cambia can cause anemia., Cambia reduces inflammation and pain, which can mask a fever and other signs used to diagnose infections. All the prescription and over-the-counter medications you take, including vitamins and supplements, Cambia can interact with other medications that also increase the risk of bleeding including warfarin, aspirin, selective serotonin reuptake inhibitors, and serotonin-norepinephrine reuptake inhibitors, Cambia can interact with certain other blood pressure medications, causing kidney problems, Cambia can interact with certain fluid pills, Cambia can increase digoxin levels, Your allergies, Your health problems, Your pregnancy or breastfeeding status and plans Cambia can interact with other medications that also increase the risk of bleeding including warfarin, aspirin, selective serotonin reuptake inhibitors, and serotonin-norepinephrine reuptake inhibitors, Cambia can interact with certain other blood pressure medications, causing kidney problems, Cambia can interact with certain fluid pills, Cambia can increase digoxin levels