Azilect is generally well tolerated. However, all medications can potentially have side effects. Some side effects that appeared in clinical trials with Rasagiline include headache, flu-like symptoms, malaise, neck pain, stomach irritation,depression, conjunctivitis, postural hypotension, constipation, vomiting, weight loss, joint pain, abdominal pain, and dyskinesia. This is not a complete list, but a list of some of the more common side effects reported. What about Rasagiline in pregnancy? There are no documented studies regarding the use of Rasagiline in pregnancy or in breast-feeding mothers.Patients taking MAO (monoamine oxidase) inhibitors or pethidine should not take Rasagiline (Azilect). There should be a minimum of 14 days from the stoppage of Rasagiline and the beginning of treatment with MAO inhibitors or pethidine.Rasagiline should not be administered at the same time as fluoxetine or fluvoxamine. Use of Rasagiline with any other antidepressants should be approached with caution. Dextromethorphan or decongestants such as pseudoephedrine should also be avoided. Because of the manner Rasagiline is removed from the body, there may also be interactions with medications such as ciprofloxacin, theophylline, entacapone, and other medications. Before starting Rasagiline, patients should inform their prescriber of all medications that they take.
